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一、基本情况:


中文全名:陈立章
职称:二级教授
学位: 医学博士
邮箱:chenliz@csu.edu.cn
部门:湘雅公共卫生澳门49码官网流行病与卫生统计学系
研究方向:围产流行病学,临床流行病学,传染流行病学,慢性非传染流行病学


二、个人学习与工作经历:

(一)教育经历 (本-硕-博)

2007.9-2008.3:渥太华大学访问学者

2001.9-2004.6:中南大学湘雅医院内科学(传染。┳ㄒ倒ザ敛┦垦,获医学博士学

1990.9-1993.6:湖南医科大学卫生系流行病学专业攻读硕士学位,获医学硕士学位

1982.9-1987.6:湖南医科大学卫生系本科学习,获医学学士学位

 

(二)研究工作经历

2019.7-至今: 任中南大学党委常委、副校长

2019.1-2019.7:任中南大学湘雅医澳门49码官网党委书记

2016.9-2019.1:任中南大学本科生院院长(正处级),2016.9晋升为二级教授

2014.6-2016.8:任中南大学研究生院招生办公室主任(正处级),2015.9转为教授,2016.7任中南大学党委委员。

2010.6-2014.6:任中南大学研究生院培养与管理办公室主任(正处级)2012.12升正高三级

2000.12-2010.5:任中南大学教务处副处长,2003.9晋升为研究员,2004.6任博士生导师

1998.11-2000.11:任湖南医科大学研究生处副处长兼培养办公室主任, 1999年任硕士研究生导师

1994.9-1998.10:任湖南医科大学研究生处学位办公室主任兼重点学科建设办公室主任19989月晋升为流行病学副教授;

1993.7-1994.8:任湖南医科大学研究生处招生办公室科员,1994年晋升讲师

1987.7-1990.8:留校任教,任湖南医科大学卫生系教师

三、研究领域与研究生培养

(一)研究领域:主要研究方向为围产流行病学,临床流行病学,传染流行病学,慢性非传染流行病学等。

主要研究内容如下:

1. 子痫前期病因及精准防控策略研究;

2. 妊娠高血压的防治策略;

3. 2型糖尿病的分子流行病学研究。

 

(二)研究生培养:

已招收培养硕士研究生66名、博士研究生30


四、科研项目

1. 湖南省财政厅,湘财教指(202275,先兆子痫病因及发病机制研究,2023.01-2024.12, 80.0万,第一负责人

2. 国家自然科学基金委员会,面上项目,82173608,基于全外显子组测序探寻先兆子痫的易感基因及其功能研究,2022/01-2025/12,55万,主持

3. 国家自然科学基金委员会,面上项目,81973137,肠道菌群及其代谢物与先兆子痫发生风险的关联及其分子机制研究,2020/01-2023/12,55万,主持

4. 湖南省科技厅,湖南省重点研发计划,2018SK2062 , 妊娠高血压的防治策略研究, 2018-2021, 100万元,第一负责人

5. 湖南省科技厅,湖南省重点研发计划,2018SK2060 , 妇幼健康大型队列及疾病防控研究, 2018-2021, 800万元,总负责人

6. 湖南省财政厅,湘财企指(2015122号,原发性高血压及肾功能损害遗传与环境影

响因素研究,2016/01-2017/12,6万,主持

7. 国家高技术研究发展计划(863计划),2014AA7024034,含铍高聚物先驱体和含铍碳化硅纤维的毒性和安全研究,2014-2015

8. 湖南省科技厅,2014SK2013,ABCB1、CYP3A5基因多态性与人群血压水平及肾功能关系的研究,2014-2016,15万,主持

9. 湖南省财政厅,湘财教指(2013240,侗族人群2型糖尿病的分子流行病学研究,2013-2015,5万,主持


五、研究成果

(一)获奖情况:

1、几种主要慢性传染病的流行特征及防治对策(谭红专、李杏莉、陈立章、陈梦施、秦家碧、陈曦、冯铁建、颜仕鹏),2018年湖南省科技进步二等奖,湖南省人民政府

 

2、HIV/AIDS、TB流行特征及基因环境影响机制研究(谭红专、李杏莉、陈立章、陈梦施、秦家碧、陈曦、颜仕鹏),2018年湖南省预防医学科学技术奖二等奖,湖南省预防医学会

 

3、乙型肝炎病毒在肝外组织的感染情况研究(陈立章,范学工,高建明,刘富强,吴成秋,莫显昆),2012年湖南省自然科学二等奖,湖南省人民政府

 

4、影响儿童智力发育因素的流行病学研究(陈立章、孙振球、林修寿、谭红专、高建民),1999年湖南省科技进步三等奖,湖南省人民政府

 

(二)论文发表情况(*为通讯作者)

1.Fan Luying, Wu Yuhang, Wei Jiehua, Xia Fan, Cai Yufeng, Zhang Senmao, Miao Junxiang, Zhou Yunzhe, Liu Chu, Yan Wei, Liu Dan, Chen Lizhang*, Wang Tingting*. Global, regional, and national time trends in incidence for migraine, from 1990 to 2019: an age-period-cohort analysis for the GBD 2019. The journal of headache and pain, 2023, 24(1):79-79

 

2.Miao Junxiang, Chen Yan, Liu Xiaoling, Ye Changxiang, Zhou Xuan, Yang Ziqi, Gong Ziqiang, Chen Lizhang*, Wang Tingting*. Maternal Body Mass Index, Gestational Weight Gain, and Risk of Cancer in Offspring: A Systematic Review and Meta-Analysis. Nutrients, 2023, 15(7)

 

3.Wei Jiehua, Wang Peiwen, Xia Fan, Miao Junxiang, Zhou Xuan, Yang Ziqi, Gong Ziqiang, Chen Lizhang*, Wang Tingting*: Time trends in cardiovascular disease mortality attributable to non-optimal temperatures in China: An age-period-cohort analysis using the Global Burden of Disease Study 2019. Frontiers in Public Health,2023, 10: 1075551

 

4.Wei Jiehua, Xia Fan, Miao Junxiang, Wang Tingting, Chen Lizhang*, Yan Xuemei*.The risk of congenital heart defects associated with corticosteroids use during the first trimester of pregnancy: a systematic review and meta-analysis. European Journal of Clinical Pharmacology, 2023, 79(1):1-11

 

5.Wu Yuhang, Xia Fan, Chen Mengshi, Zhang Senmao, Yang Ziqi, Gong Ziqiang, Zhou Xuan, Chen Lizhang*, Wang Tingting*. Disease burden and attributable risk factors of neonatal disorders and their specific causes in China from 1990 to 2019 and its prediction to 2024. Bmc Public Health,2023, 23(1)

 

6.Yang Ziqi, Zhou Xuan, Gong Ziqiang, Zhang Senmao, Liu Xiaoling, Chen Yan, Ye Changxiang, Chen Lizhang*, Wang Tingting*. Effect of hypertensive disorders of pregnancy on pubertal development in daughters and sons: a systematic review and meta-analysis. Journal of Human Hypertension,2023, 37(1):20-27

 

7.Chen Yan, Wang Tingting, Liu Xiaoling, Ye Changxiang, Xing Dexiu, Wu Rong, Li Fang, Chen Lizhang*. Low molecular weight heparin and pregnancy outcomes in women with inherited thrombophilia: A systematic review and meta-analysis. Journal of Obstetrics and Gynaecology Research,2022, 48(8):2134-2150

 

8.Gong Ziqiang, Xing Dexiu, Wu Rong, Zhang Senmao, Ye Changxiang, Chen Yan, Liu Xiaoling, Chen Lizhang*, Wang Tingting*.Prognostic value of N-terminal pro-form B-type natriuretic peptide (NT-proBNP) in patients with congenital heart disease undergoing cardiac surgery: a systematic review and meta-analysis of cohort studies. Cardiovascular Diagnosis and Therapy, 2022,12(6): 853-867

 

9.Luo Zhicheng, Zhu Xidi, Hu Yingyun, Yan Shipeng*, Chen Lizhang*. Association between dietary inflammatory index and oral cancer risk: A systematic review and dose-response meta-analysis. Frontiers in Oncology,2022,12: 920452

 

10.Zhang Senmao, Liu Xiaoying, Yang Tubao, Wang Tingting, Chen Lizhang*, Qin Jiabi*. Association of maternal dietary habits and ADIPOQ gene polymorphisms with the risk of congenital heart defects in offspring: a hospital-based case-control study. European Journal of Clinical Nutrition,2022, 76(3):373-381

 

11.Zhang Senmao, Qiu Xing, Qin Jiabi, Song Xingli, Liu Yiping, Wei Jianhui, Sun Mengting, Shu Jing, Wang Tingting, Chen Lizhang*, Jiang Yurong*.Effects of Maternal Pre-Pregnancy BMI and Gestational Weight Gain on the Development of Preeclampsia and Its Phenotypes: A Prospective Cohort Study in China. Journal of Clinical Medicine,2022, 11(19)

 

12.Zhang Senmao, Qiu Xing, Wang Tingting, Chen Letao, Li Jinqi, Diao Jingyi, Li Yihuan, Qin Jiabi, Chen Lizhang*, Jiang Yurong*.Hypertensive Disorders in Pregnancy Are Associated With Congenital Heart Defects in Offspring: A Systematic Review and Meta-Analysis. Frontiers in Cardiovascular Medicine,2022, 9: 842878

 

13.Zhou Xuan, Hu Yang, Yang Ziqi, Gong Ziqiang, Zhang Senmao, Liu Xiaoling, Chen Yan, Ye Changxiang, Chen Lizhang*, Wang Tingting*.Overweight/Obesity in Childhood and the Risk of Early Puberty: A Systematic Review and Meta-Analysis. Frontiers in Pediatrics,2022, 10: 795596

 

14.刘小玲,陈艳,叶长翔,陈立章*,王婷婷*.妊娠期体重增加与后代成年超重和肥胖发生风险:系统综述和Meta分析.中华疾病控制杂,2022,26(05): 583-588.

 

15.陈艳,王婷婷,刘小玲,叶长翔,陈立章*.妊娠期体质量增加与产后抑郁症关系的Meta分析.实用妇产科杂志,2022,38(03):233-237.

 

16.Li Fang, Chen Lizhang*. The Association between Trajectories of Anthropometric Variables and Risk of Diabetes among Prediabetic Chinese. Nutrients,2021, 13(12)

 

17.Li Fang, Lin Qian, Li Mingshu, Chen Lizhang*, Li Yingjun*.The Association between Blood Pressure Trajectories and Risk of Cardiovascular Diseases among Non-Hypertensive Chinese Population: A Population-Based Cohort Study. International Journal of Environmental Research and Public Health,2021, 18(6)

 

18.Li Fang, Qin Jiabi, Zhang Senmao, Chen Lizhang*. Prevalence of hypertensive disorders in pregnancy in China: A systematic review and meta-analysis. Pregnancy Hypertension-an International Journal of Womens Cardiovascular Health,2021, 24:13-21

 

19.Li Fang, Wang Tingting, Chen Letao, Zhang Senmao, Chen Lizhang*, Qin Jiabi*.Adverse pregnancy outcomes among mothers with hypertensive disorders in pregnancy: A meta-analysis of cohort studies. Pregnancy Hypertension-an International Journal of Womens Cardiovascular Health,2021, 24:107-117

 

20.Liu Xiaoling, Chen Yan, Ye Changxiang, Xing Dexiu, Wu Rong, Li Fang, Chen Lizhang*, Wang Tingting*.Hereditary thrombophilia and recurrent pregnancy loss: a systematic review and meta-analysis. Human Reproduction, 2021, 36(5):1213-1229

 

21.Qin Yi, Chen Lu, Chen Lizhang*.Identification and verification of key cancer genes associated with prognosis of colorectal cancer based on bioinformatics analysis. Zhong nan da xue xue bao Yi xue ban = Journal of Central South University Medical sciences, 2021, 46(10):1063-1070

 

22.颜雪梅,孔繁娟,王爱华,李芳,陈立章*.6579例妊娠期高血压疾病孕产妇的患病情况及发生危重情况的影响因素.中南大学学报(医学版) ,2021,46(08):814-821

 

23.覃异,陈璐,陈立章*.基于生物信息学分析并验证一组与结直肠癌预后相关的基因.中南大学学报(医学版),2021,46(10):1063-1070

 

24.颜雪梅,孔繁娟,王爱华,李芳,陈立章*.2012—2019年妊娠期高血压疾病流行现状及妊娠结局分析. 中国生育健康杂志,2021,(03),252-256

 

25.叶长翔,陈生宝,王婷婷,张森茂,秦家碧,*陈立章*.早产危险因素的前瞻性队列研究.中国当代儿科杂志2021, (12),1242-1249

 

26.Wu Rong, Wang Tingting, Gu Runhui, Xing Dexiu, Ye Changxiang, Chen Yan, Liu Xiaoling, Chen Lizhang*.Hypertensive Disorders of Pregnancy and Risk of Cardiovascular Disease-Related Morbidity and Mortality: A Systematic Review and Meta-Analysis. Cardiology, 2020, 145(10):633-647

 

27.Xing Dexiu, Wu Rong, Chen Lizhang*, Wang Tingting*.Maternal use of antidepressants during pregnancy and risks for adverse perinatal outcomes: a meta-analysis. Journal of Psychosomatic Research, 2020, 137

 

28.Zhao Lijuan, Chen Lizhang*, Yang Tubao, Wang Tingting, Zhang Senmao, Chen Letao, Ye Ziwei, Luo Liu, Qin Jiabi*.Birth prevalence of congenital heart disease in China, 1980-2019: a systematic review and meta-analysis of 617 studies. European Journal of Epidemiology, 2020, 35(7):631-642

 

29.Zhou Wei, Liu Qian, Yu Yu, Xiao Shuiyuan, Chen Lizhang*, Kaveh Khoshnood, Zheng Shimin.Proxy reliability of the 12-item World Health Organization Disability Assessment Schedule II among adult patients with mental disorders. Quality of Life Research.2020;10.

 

30.Wei Zhou, Yu Yu, Xinyi Zhao, Shuiyuan Xiao* and Lizhang Chen*. Evaluating China’s mental health policy on local-level promotion and implementation: a case study of Liuyang Municipality. BMC Public Health, 2019: 19--24

 

31.Shiyu Cao , Fuqiang Liu, Tingting Wang , Yaqing Tan ,Shujun Liu , Yuan Liu , Lidong Gao ,* Lizhang Chen *. New patterns emerge after a sustained increase in the incidence of hepatitis C virus infection from 2004 to 2017: a joinpoint regression analysis. Public health, 2019,170:49-56

 

32.Li Q, Yin Z, Wang T, Chen L*, Li Z*. Gemcitabine and cisplatin regimen facilitates prognosis of advanced nasopharyngeal carcinoma. Cancer Med. 2018, 7(7): 2985-2992

 

33.Wang T, Fu H, Kaminga AC, Li Z, Guo G, Chen L*, Li Q*. Prevalence of depression or depressive symptoms among people living with HIV/AIDS in China: a systematic review and meta-analysis. BMC Psychiatry 2018, 18(1):160

 

34.Liu Z, Wang T, Liu Y, Wang A, Xie D, Kong F, Xiong L, Chen L*, Wang H*. Evaluating the progress to eliminate mother-to-child transmission (MTCT) of syphilis in Hunan Province, China: A study based on a health service delivery model.Plos one, 2018, 13(9): e0203565.

 

35.Wei Zhou, Yu Yu, Mei Yang, Lizhang Chen and Shuiyuan Xiao*. Policy development and challenges of global mental health: a systematic review of published studies of national-level mental health policies. BMC Psychiatry, 2018,18:138

 

36.CaiXiao Jiang,Shujun Liu,Shuxia Liu,ZhanZhan Li, Peng Chen, LiZhang Chen*. Association between the Interleukin-10-1082G/A, ?592C/A, 819C/T Gene Polymorphism and HIV-1 Susceptibility: A Meta-analysis.AIDS Research and Human Retroviruses,2017,33(1):61-67 (SCI)

 

37.Zhanzhan Li, Peng Chen, Tao Zhou, Xiaofang Chen,Lizhang Chen *.Association between CYP3A5 genotypes with hypertension in Chinese Han population: A casecontrol study.Clinical and Experimental Hypertension.2017, 39(3): 235–240

 

38.Zhi Yin, Jin Zou, Qiongxuan Li, Lizhang Chen*. Diagnostic value of FIB-4 for liver fibrosis in patients with hepatitis B: a meta-analysis of diagnostic test.Oncotarget. 2017,1: 1-10

 

39.Wang T, Liu K, Li Z, Xu Y, Liu Y, Shi W, Chen L*. Prevalence of attention deficit/hyperactivity disorder among children and adolescents in China: a systematic review and meta-analysis. BMC Psychiatry, 2017, 17(1): 32

 

40.Huiqing Wang,Tingting Wang,Wenpei Shi, Yuan Liu, Lizhang Chen* and Zhanzhan Li*.Comprehensive analysis on diagnostic value of circulating miRNAs for patients with ovarian cancer.Oncotarget, 2017, 8(39): 66620-66628

 

41.Tingting Wang, Yuan Liu, Zhanzhan Li, Kaihua Liu, Yang Xu, Wenpei Shi,Lizhang Chen*. Prevalence of intimate partner violence (IPV) during pregnancy in China: A systematic review and meta-analysis. PLOS ONE. 2017,10:1-17

 

42.Zhanzhan Li, Tao Zhou, Yanyan Li, Peng Chen & Lizhang Chen*.Anemia increases the mortality risk in patients with stroke: A meta-analysis of cohort studies. Scientific Reports, 2016,6:26636

 

43.Zhan-Zhan Li, Liang-Fang Shen, Yan-Yan Li, Peng Chen, Li-Zhang Chen*.Clinical utility of microRNA-378 as early diagnostic biomarker of human cancers: a meta-analysis of diagnostic test.Oncotarget, 2016,7(36): 58569-58578

 

44.Lizhang Chen, Zhanzhan Li, Yanyan Li ,Jing Xue, Peng Chen, Shipeng Yan, Caixiao Jiang, Yingyun Hu, Xing Qiao5. Red Cell Distribution Width and Inappropriateness of Left Ventricular Mass in Patients with Untreated Essential Hypertension.PLOS ONE,2015,10(3):e120300

 

45.Shipeng Yan,Lizhang Chen*, Wenqiong Wu, Zhongxi Fu, Heng Zhang, Zhanzhan Li, Chenchao Fu, Jingsong Mou, Jing Xue, Yingyun Hu. Early versus Delayed Antiretroviral Therapy for HIV and Tuberculosis Co-Infected Patients: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.PLOS ONE, 2015,10(5):e127645

 

46.ZhanZhan Li and LiZhang Chen*. Comparison of ultrasound-guided modified Seldinger technique versus blind puncture for peripherally inserted central catheter: a meta-analysis of randomized controlled trials.Critical Care, 2015,19:64

 

47.Zhanzhan Li, Yanyan Li, Lizhang Chen, Peng Chen, Yingyun Hu. Prevalence of Depression in Patients With Hypertension:A Systematic Review and Meta-Analysis.Medicine(Baltimore),2015,94(31):e1317

 

48.Cai Xiao Jiang, Zhan Zhan Li, Peng Chen, Li Zhang Chen. Prevalence of Depression Among College-Goers in Mainland China:A Methodical Evaluation and Meta-Analysis.Medicine(Baltimore), 2015,94(50):e2071

 

49.CaiXiao Jiang, ZhanZhan Li, Peng Chen, LiZhang Chen. The Seroprevalence of Toxoplasma gondii in Chinese Population With Cancer A Systematic Review and Meta-analysis.Medicine(Baltimore), 2015,94(50):e2274 IF=5.723

 

50.ZhanZhan Li, Jing Xue, Peng Chen, LiZhang Chen*, Shi-Peng Yan, LiYa Liu. Prevalence of nonalcoholic fatty liver disease in mainland of China: a meta-analysis of published studies. Journal of Gastroenterology and Hepatology, 2014,29(1):42-51

 

51.Zhan-Zhan Li, Ya-Ming Li2, Xian-Yang Lei, Dan Zhang, Li Liu, Si-Yuan Tang, Lizhang Chen*. Prevalence of Suicidal Ideation in Chinese College Students: A Meta-Analysis. PLoS One, 2014,9(10):e104368.

 

52.Liya LIU, Lizhang Chen*, Zhanzhan LI, Liang LI, Jian QU, Jing XUE.Association between Gene Polymorphisms of Seven Newly Identified Loci and Type Diabetes and the Correlate Quantitative Traits in Chinese Dong Populations.Iranian J Publ Health, 2014,43(10):1345-1355

 

六、教学

(一)承担的主要课程:

1.流行病学

2.循证医学

3.临床流行病学


(二)教材编写:

1.副主编、《高等澳门49码官网新型冠状病毒肺炎防控指南(20203月)》、人民卫生出版社、2020

2.主编、《循证医学》、高等教育出版社、2015

 

3.主编、《管理流行病学》、中南大学出版社、2013

 

4.主编、《循证医学与实践》、中南大学出版社、2012

 

5.副主编、《临床流行病学》、中南大学出版社、2010

 

6.副主编、《临床流行病学》、中南大学出版社、2004

 

7.参编、《社区医学》、人民卫生出版社、2001



七、社会兼职:

1.临床流行病学湖南省重点实验室主任

 

2.湖南省医学科教学会副会长

 

3.中国学位与研究生教育学会医药科工作委员会委员

 

4.教育部高等澳门49码官网实验室建设与实验教学指导委员会委员

 

5.中国高等教育学会理事

 

6. 全国医学专业学位与研究生教育指导委员会公共卫生分委员会委员

 

7. 湖南省普通高校精品课程建设专家委员会副主任委员


 

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